![]() Medications presented in this section are intended to provide general information about possible treatment. Food-offered 24 hours after initiation of treatment.Drinking water should be available at all times.Fluid therapy to maintain hydration and electrolyte balance.Low red blood cell count (known as “anemia”), blood in the urine (hematuria), or presence of hemoglobin in the urine (known as “hemoglobinuria”)-may require whole blood transfusion.The veterinarian will induce vomiting (known as “emesis”) and may perform flushing of the stomach (known as “gastric lavage”)-useful within 4–6 hours of ingestion of acetaminophen.A nomogram of serum APAP concentration vs hours post-ingestion can assist in determining risk. For an acute overdose, most adults must ingest about 12g or more acetaminophen (APAP) before risk of serious hepatotoxicity is of concern. Gentle handling-imperative for clinically affected pets A review of the typical clinical course, diagnosis and treatment of acetaminophen toxicity is provided.With dark or bloody urine or yellowish discoloration of skin and moist tissues of the body (known as “jaundice” or “icterus”)-inpatient care.With methemoglobinemia (abnormal compound in the blood that disrupts the ability of the red blood cells to carry oxygen to the body)-must evaluate promptly inpatient care.Simultaneous administration of other glutathione-depressing drugs.Nutritional deficiencies of glucose and/or sulfate.Chocolate-colored urine due to the presence of blood in the urine (known as “hematuria”) and the presence of methemoglobin in the urine (known as “methemoglobinuria”). ![]() Fluid buildup (edema)-face, paws, and possibly forelimbs after several hours.Rapid breathing (known as “tachypnea”) and bluish discoloration of skin and moist tissues of body (known as “cyanosis”) due to a abnormal compound (methemoglobin) in the blood (condition known as “methemoglobinemia”) that disrupts the ability of the red blood cells to carry oxygen to the body.Darkened mucous membranes (moist tissues of body, such as gums). ![]()
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